Just thought I'd post a couple screen caps from a recent Venture Brothers rerun. The flaming guy has opened a gate to Hell, and this thing comes through. Now of course, Cthulhu is not (as far as I know) a denizen of Hell, but the homage is clear.
The flaming guy is the first one to die. The one who opens the gate to Hell is always the first to die. It's basic Black Magic 101.